![]() Percent identity between a putative human mitogen-activated protein kinase catalytic domain polypeptide variant and an amino acid sequence of SEQ ID NO:2 is determined by conventional methods. Preferably, naturally or non- naturally occurring human mitogen-activated protein kinase catalytic domain polypeptide variants have amino acid sequences which are at least 55, 60, 65, or 70, preferably about 75, 80, 85, 90, 95, 96, 97, 98, or 99% identical to the amino acid sequence shown in SEQ ID NO:2 or a fragment thereof. Human mitogen-activated protein kinase catalytic domain polypeptide variants which are biologically active, e.g., retain an enzymatic activity also are human mitogen- activated protein kinase catalytic domain polypeptides. A61K38/00- Medicinal preparations containing peptides.A61K- PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES.A61- MEDICAL OR VETERINARY SCIENCE HYGIENE.C12Y207/00- Transferases transferring phosphorus-containing groups (2.7).C12N9/1205- Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g.C12N9/12- Transferases (2.) transferring phosphorus containing groups, e.g.C12N9/00- Enzymes Proenzymes Compositions thereof Processes for preparing, activating, inhibiting, separating or purifying enzymes.C12N- MICROORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA.C12- BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION OR GENETIC ENGINEERING.Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Priority claimed from US35286802P external-priority Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag Publication of WO2003064639A1 publication Critical patent/WO2003064639A1/en Links Inventor Alex Smolyar Original Assignee Bayer Healthcare Ag Priority date (The priority date is an assumption and is not a legal conclusion. Google Patents Regulation of human mitogen-activate protein kinase catalytic domainÄownload PDF Info Publication number WO2003064639A1 WO2003064639A1 PCT/EP2003/001023 EP0301023W WO03064639A1 WO 2003064639 A1 WO2003064639 A1 WO 2003064639A1 EP 0301023 W EP0301023 W EP 0301023W WO 03064639 A1 WO03064639 A1 WO 03064639A1 Authority WO WIPO (PCT) Prior art keywords protein kinase mitogen catalytic domain activated protein kinase catalytic Prior art date Application number PCT/EP2003/001023 Other languages French ( fr) Google Patents WO2003064639A1 - Regulation of human mitogen-activate protein kinase catalytic domain WO2003064639A1 - Regulation of human mitogen-activate protein kinase catalytic domain ![]()
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